Effect of Ethanol Extract of <i>Indigofera tinctoria</i> Linn (Fabaceae) on Lithium/Pilocarpine-Induced Status Epilepticus and Oxidative Stress in Wistar Rats

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Effect of Ethanol Extract of Indigofera tinctoria Linn (Fabaceae) on Lithium/Pilocarpine-Induced Status Epilepticus and Oxidative Stress in Wistar Rats

Purpose: Indigofera tinctoria Linn. of the Fabaceae family is claimed to be useful in the treatment of a variety of epileptic disorders in Indian traditional system of medicine. The present study was designed to verify this claim. Methods: Status epilepticus was induced in male albino rats of Wistar strain by administration of pilocarpine (30 mg/kg, i.p.) 24 h after injection of lithium chlorid...

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protective effect of hydro alcoholic extract of Aloysia citriodora against ethanol-induced hepatotoxicity in male Wistar rats via assessment of inflammatory and oxidative stress markers

Objective: Chronic ethanol consumption has significant negative effects on liver tissue. Mechanisms of ethanol toxicity include oxidative stress and inflammation. The antioxidant and anti-inflammatory properties of the lemon verbena have been proven in studies. The aim of this study was to evaluate the protective effect of hydro alcoholic extract of Aloysia citriodora (AC) on ethanol-induced he...

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Effect of Argemone mexicana (L.) against lithium-pilocarpine induced status epilepticus and oxidative stress in Wistar rats.

Argemone mexicana (L.) has a role in the treatment of epileptic disorders in Indian traditional system of medicine. We studied its effect on induced status epilepticus (SE) and oxidative stress in rats. SE was induced in male albino rats by administration of pilocarpine (30 mg/kg, ip) 24 h after injection of lithium chloride (3 mEq/kg, ip). Different doses of the ethanol extract of A. mexicana ...

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Modulatory effect of Tinospora cordifolia extract on Cd-induced oxidative stress in Wistar rats

BACKGROUND Cadmium (Cd), a nonessential heavy metal, is a major environmental and public health concern. Oxidative stress plays an important role in Cd-induced kidney dysfunction. Tinospora cordifolia, a medicinal plant rich in phytochemicals, possesses antioxidant activity. The objective of the present study was to assess the protective effect of Tinospora cordifolia-stem methanolic extract (T...

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ژورنال

عنوان ژورنال: Tropical Journal of Pharmaceutical Research

سال: 2010

ISSN: 1596-9827,1596-5996

DOI: 10.4314/tjpr.v9i2.53702